The cause of premature birth is often unknown. However, certain maternal health conditions can contribute to the birth of a premature baby, such as diabetes, high blood pressure, heart disease, or kidney disease. [2,4] Since preterm birth is linked to the birth of premature babies, all factors that increase the likelihood of preterm labor are considered causes of premature birth. These factors include: Multiple pregnancies, such as twins or triplets. Severe stress. Infections, such as urinary tract infections or amniotic membrane infections. Weak or prematurely dilated cervix, or congenital uterine abnormalities. A previous preterm birth. Poor maternal nutrition before or during pregnancy. Preeclampsia. Vaginal bleeding. Blood clotting disorders. [1,2] Other factors associated with preterm birth and premature babies include: Maternal age, if younger than 17 or older than 35. Smoking. Short intervals between pregnancies, meaning conception occurs less than a year after a previous pregnancy. Excessive alcohol consumption or drug addiction. Lack of prenatal care for the mother and baby. Poor socioeconomic conditions of the mother. [1,2,4]